Tensile Properties

Tensile Properties of Randomly Oriented Collagen Gels of Varying Concentration 2 ABSTRACT Proteins, such as collagen, are commonly strength biomaterials for spend in health check products. Examples include drippy skin, bone, tendon, and other body tissues. The addition of a protein coating on a biomaterial could provide beneficial molecular(a) and physical properties. Little preceding(prenominal) testing has been done to absorb the tensile properties of collagen gels, characteristics that go away help in the development of a novel polymer/collagen biomaterial. The accent of this investigation is to determine the flexile moduli, eventual(prenominal) puree, and other tensile properties of collagen hydrogels with concentrations variable from 5-7 mg/mL. Collagen gel prototypes will be tested use a uniaxial test syllabus on an MTS 858 Mini Bionix II test frame. Gels were made on ice from collagen isolated from rat-tail tendons and change state in 0.02M acetic acid. The collagen was brought to physiological osmolarity using NaHCO3, 10x alpha-MEM, and Hepes. The resulting mixture was equalized at a pH of 7.4 using NaOH and diluted to its final slew using H20. Gels were formed into a standard testing specimen by pouring the gel mixture into a silicone mold and allowing it to solidify by warming to physiological temperature. Gels were and so subjected to uniaxial tension until failure at two independent personal line of credit rates to measure elastic modulus, ultimate stress, and other properties. Results indicated a marked variability in both ultimate stress and elastic modulus over the dress of concentrations used. Ultimate strength set ranged from .317 kPa to 1.85 kPa and elastic modulus from 10.392 Pa to 39.867 Pa over the three divergent concentrations. Key Terms: automatonlike testing, biomaterials, tendon, viscoelasticity, collagen, hydrogel 3 BACKGROUND T and m he tensile properties of connective tissues in the easy body de pend on their composition icrostructural org! anization of their material...If you plow for to get a full essay, order it on our website: OrderEssay.net

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